主要科研成果与奖励(主持项目、获奖、著作、代表性论文) 近年来,先后主持国家自然科学基金2项、山东省省属优青项目1项,山东省科技攻关项目1项、上海市科技发展项目1项;目前以通讯作者或第一作者身份在Bioorg. Chem.,Bioorg. Med. Chem. Lett.等国际著名期刊发表SCI论文49篇,以第一发明人获授权国家发明专利4项,获2018年山东省优秀研究生导师称号。 主持科研项目 1、山东省自然科学省属优青,2019.09-2022.8,30万。 2、国家自然科学基金面上项目,2017.01-2020.12,63万。 代表性论文 (1) Lei Zhou, et al., Cheng-Shi Jiang*. A new endoplasmic reticulum (ER)-targeting fluorescent probe for the imaging of cysteine in living cells. J. Fluoresc., 2020, DOI: 10.1007/s10895-020-02615-x. (2) Yueqi Zhao, et al, Juan Gao*, Cheng-Shi Jiang*, Xia Wang*. One and two proton-transfer mechanisms coexist in one active site. J. Phys. Chem. B., 2020, 124 (31), 6699-6708. (3) Kaiming Wang, et al, Cheng-shi Jiang*, Luís Alexandre Muehlmann*.A xanthene derivative, free or associated to nanoparticles, as a new potential agent for anticancer photodynamic therapy. J. Biomat. Sci.: Polym. E., 2020, DOI: 10.1080/09205063.2020.1788370. (4) Yu-Ying Zhang, et al., Cheng-Shi Jiang*, Hua Zhang*. Synthesis and evaluation of 1,2,4-oxadiazole derivatives as potential anti-inflammatory agents that inhibit NF-κB activation. Bioorg. Med. Chem. Lett., 2020, 30, 127373. (5) Lei Zhou, et al., Juan Zhang*, Kai-Ming Wang*, Cheng-Shi Jiang*. A highly sensitive endoplasmic reticulum-targeting fluorescent probe for the imaging of endogenous H2S in live cells. Spectrochim Acta A Mol. Biomol. Spectrosc., 2020, 240, 118578. (6) Yong-Xi Ge, et al., Cheng-Shi Jiang*. Synthesis and biological evaluation quinoline/cinnamic acid hybrids as amyloid-beta aggregation inhibitors. Monstch. Chem., 2020, 151, 845-852. |