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  科研项目 更多>>      

序号

项目名称

项目来源

起止时间

主持人

1

天然药物化学

国家自然科学基金优秀青年科学基金项目

2014.01-2016.12

张华

2

三种割舌树属植物中新颖活性结构的发现与研究

国家自然科学基面上项目

2013.01-2016.12

张华

3

山东省高等学校优势学科人才团队培育计划

山东省高等学校优势学科人才团队培育计划

2016.01-2020.12

张华

4

山东省泰山学者青年专家计划

山东省人民政府

2017.01-2021.12

张华

5

豌豆光系统I的捕光天线复合体光保护机制的研究

国家自然科学基金面上项目

2017.01-2020.12

秦晓春

6

光合膜复合物结构、功能及生物发生

国家自然科学基金优秀青年科学项目

2017.01-2019.12

秦晓春

7

加工食品中生物危害物多元识别与控制技术

国家863项目子课题

2012.01-2015.12

黄加栋

8

基于基因工程单链抗体的食品中小分子化学污染物快速检测压电免疫传感器研究

国家自然科学基金面上项目

2012.01-2015.12

黄加栋

9

基于纳米增效分子印迹膜的农药多残留高通量快速检测传感器微阵列研究

国家自然科学基金面上项目

2010.01-2012.12

黄加栋

10

基于糖基功能化分子印迹聚合物的细菌毒素检测生物传感器

国家自然科学基金中韩合作与交流项目

2009.06-2011.05

黄加栋

11

农产品中痕量环境内分泌干扰物残留检测的纳米增效分子印迹仿生传感技术研究

国家自然科学基金青年基金

2008.01-2010.12

黄加栋

12

基于基因工程单链抗体的重要真菌毒素检测研究

国家863专题子课题

2007.10-2010.10

黄加栋

13

纳米增效分子印迹膜为感受器的农药多残留高通量快速检测传感芯片

山东省科技发展计划项目

2010.12-2012.12

黄加栋

14

基于纳米增效分子印迹膜的痕量重要真菌毒素快速检测仿生传感系统

山东省优秀中青年科学家科研奖励基金项目

2009.12-2012.12

黄加栋

15

大肠埃希氏菌S-腺苷高半胱氨酸核苷酶的作用机制及其作为抗菌药物靶点的探究

国家自然科学基金面上项目

2014.01-2017.12

谷劲松

16

生物一类新药重组人神经生长因子变异体及其创新适应症的研究

国家新药创制重大专项

2012

谷劲松

17

YabC的甲基转移酶功能及其在大肠杆菌细胞分裂过程中的作用

国家自然科学基金面上项目

2011.01-2013.12

谷劲松

18

新型红细胞代用品的研制

山东省科技发展计划项目

2010.01-2013.10

谷劲松

19

大肠杆菌YabC蛋白的甲基转移酶功能及其在细胞分裂中的作用

山东省自然科学基金

2010.12-2013.12

谷劲松

20

S-腺苷高半胱氨酸核苷酶为耐药病原菌新靶标的抗菌药物的研发

山东省重点研发项目

2015.10-2017.10

谷劲松

21

F值玉米寡肽的分离制备、结构表征及其对酒精性肝损伤的保护作用

山东省自然基金

2015.12-2017.12

王元秀

22

土壤杆菌M503低分子量β-13-葡聚糖生物絮凝剂合成相关基因的克隆及功能分析

国家自然科学基金青年基金

2012.01-2014.12

李强

23

多糖生物絮凝剂合成基因的克隆及功能分析

山东省中青年科学家奖励基金

2007.12-2010.12

李强

24

赖草地下根茎网梯级分蘖基因调控机理研究

国家自然科学基金面上项目

2014.01-2014.12

何文兴

25

异源性核糖核蛋白E1调控动脉粥样硬化斑块内血管生成的作用及机制研究

国家自然科学基金面上项目

2017.01-2020.12

孟宁

26

利用新型吡唑衍生物研究血管内皮细胞自噬与血管生成的关联机制

国家自然科学基金青年基金

2013.01-2015.12

孟宁

27

海洋生物活性碱Fascaplysin调节血管内皮细胞自噬的机制研究

山东省优秀中青年科学家科研奖励基金

2013.10-2015.10

孟宁

28

一种姜黄素-纳米颗粒在治疗动脉粥样硬化中的应用研究

山东省科技发展计划

2013.10-2016.10

孟宁

29

植物源烟水对丹参次生代谢产物积累的影响及“smoke signals”机制研究

国家自然科学基金面上项目

2017.01-2020.12

周洁

30

土壤因子镧促进丹参有效物质积累的信号转导和分子机制研究

国家自然科学基金青年基金

2014.01-2016.12

周洁

31

金银花质量特征和商品规格研究

中央本级重大增减支项目子课题

2013.01-2014.12

周洁

32

植物源烟水促进白花丹参生物量和药效成分积累及机制研究

山东省自然科学基金项目

2014.01-2016.12

周洁

33

山东太子参道地产区抢救、资源保护及产区重建关键技术研究

山东省科技发展计划项目

2015.04-2017.03

周洁

34

新型非甾体类盐皮质激素受体拮抗剂-(3R)--O-甲基毛狄泼老素类似物的设计、合成及其构效关系研究

国家自然科学基金青年基金

2014.01-2016.12

江成世

35

海洋天然产物Hyrtioseragamine B的合成、结构修饰及其多靶向抗阿尔茨海默症构效关系研究

国家自然科学基金面上项目

2017.01-2020.12

江成世

36

基于显微策略的两种山橙属植物中微量生物碱的发现及其抗肿瘤活性研究

国家自然科学基金青年基金

2013.01-2015.12

方磊

37

基于高速逆流色谱-生物捕集技术的中药抗氧化活性成分研究

山东省自然科学基金项目

2013.01-2015.12

方磊

38

微量生物碱类抗肿瘤活性物质的高效富集与快速制备技术及示范研究

山东省科技发展计划项目

2014.04-2016.12

方磊

39

小麦盐诱导TaWRKY转录因子的功能及耐盐机制研究

国家自然科学基金青年基金

2010.1-2013.12

秦余香

40

小麦盐诱导高效表达脱水素基因及其启动子的克隆与鉴定(

山东省优秀中青年科学家科研奖励基金

2011.07-2014.07

 

秦余香

41

利用节杆菌B4胞外多糖研究多糖抑制铜绿假单胞菌生物膜形成的关键机制

国家自然科学基金青年基金

2014.01-2016.12

李玉梅

42

主要农作物品质性状形成的分子基础

科技部,国家重点研发计划七大农作物育种重点专项子课题

2016.07-2020.12

李慧

43

玉米籽粒基因表达异方差性的遗传机理研究

国家自然科学基金青年基金

2014.12-2015.07

李慧

44

玉米籽粒基因对共表达模式变化的遗传机理研究,

山东省优秀中青年科学家科研奖励基金

2014.12-2016.12

李慧

45

联苄类化合物的发现与逆转肿瘤多药耐药活性研究

国家自然科学基金青年基金

2015.01-2017.12

刘娜

46

P-gp蛋白为靶点的抗肿瘤联苄类化合物的分离、鉴定与活性研究

山东省自然科学基金

2015.01-2016.12

刘娜

47

基于共培养的两株柳珊瑚共附生真菌活性次级代谢产物的研究

国家自然科学基金青年基金

2016.01-2018.12

鲍洁

48

生物诱导作用下海洋真菌A. sclertoiorum SCSGAF 0053活性次级代谢产物的研究,BS2015HZ005

山东省优秀中青年科学家科研奖励基金

2015.07-2017.07

鲍洁

49

多功能夹芯型纳米复合物探针构建及其应用于原位监测药物可控释放和肿瘤光热化疗研究

国家自然科学基金青年基金

2015.01-2017.12

王玉

50

高灵敏、可重现的新型SERS核壳纳米结构探针构建与循环肿瘤细胞检测的SERS生物传感新方法研究

山东省优秀中青年科学家科研奖励基金

2014.12-2016.12

王玉

51

利用代谢拨动开关调控大肠杆菌芳香型氨基酸的合成

国家自然科学基金青年基金

2017.01-2019.12

古鹏飞

52

大肠杆菌基因组随机拷贝数整合系统的建立和应用

中国博士后科学基金面上项目

2014.05-2016.05

古鹏飞

53

多氯联苯(PCBs)暴露对非酒精性脂肪肝的影响及相关分子机制研究

国家自然科学基金青年基金

2016.1-2018.12

单秋丽

54

类二噁英多氯联苯(DLPCBs)暴露对非酒精性脂肪肝的影响及其潜在分子机制研究

山东省自然科学基金

2015.7-2017.6

单秋丽

55

噬菌体SWU1杀菌过程中ROS的作用及产生机制研究

国家自然科学基金青年基金

2017.01-2019.12

樊祥宇

56

基于噬菌体特有蛋白分子的新型抗菌剂研究

山东省博士基金

2014.12-2016.12

樊祥宇

57

人参皂苷的系统制备及其神经保护的构效关系研究

国家自然科学基金青年基金

2015.01-2017.12

高娟

58

鞘脂合成调控因子Orm1在球孢白僵菌中的功能鉴定及其致病机理研

国家自然科学基金青年基金

2017.01-2019.12

王娟娟

59

小桃儿七中5α-构型蟾毒配基类化合物的快速发现及抗肿瘤构效关系研究

国家自然科学基金青年基金

2017.01-2019.12

杨凤英

60

ADAMTS18在软骨细胞分化中的作用及其机制研究(31501104

国家自然科学基金青年基金

2016/01-2018/12

张玉颖

61

一个长链非编码RNA的鉴定及其调节血管内皮细胞自噬的机制研究(31501122

国家自然科学基金青年基金

2016.01-2018.12

葛迪

62

基于枯否细胞吞噬作用研究抗体-毒素偶联药物T-DM1肝脏毒性的机制

国家自然科学基金青年基金

2017.01-2019.12

李宁

63

稀土上转换纳米颗粒对间充质干细胞命运的调控

国家自然科学基金青年基金

2016.01-2018.12

任娜

64

一种绿色抗菌肽类饲料添加剂

山东省科技发展计划项目

2012/01-2014/12

李殿香

65

一种抗耐药菌的新型抗菌肽药物研究

山东省医药卫生科技发展计划项目

2011/09-2013/12

李殿香

66

家蝇酚氧化酶原激活酶功能分析

山东省自然科学基金项目

2011/07-2014/07

李殿香

67

抗癌药物紫杉醇PEG-PCL多不饱和脂肪酸衍生化纳米粒制剂的研究

山东省优秀中青年奖励基金项目

2011.07-2014.07

冯润良

68

乳链菌肽/蜜蜂肽工程菌的构建及其生物制品产业化示范

山东省科技发展计划项目

2013.01-2015.12

叶春江

69

利用啤酒废酵母制备富硒酵母

山东省教育厅科技处

2012-2015

孙纳新

70

发酵法生产D-核糖的生物反应过程的建模与控制

山东省自然科学基金

2014.01-2016.12

杨新超

71

诱导人源多潜能干细胞过程中关键转录因子Sox2及其复合物的结构研究

山东省博士基金

2014.12-2016.12

李连博

 

 
  科技论文 更多>>      

序号

论文名称

期刊名(期、卷、页)

收录情况及IF

首位或

通讯作者

1

Structural basis for energy transfer pathways in the plant PSI-LHCI supercomplex

Science   2015,

348 (6238) :989

SCI

IF:34.661

秦晓春

2

Isolation        and characterization of a PSI-LHCI super-complex and its sub-complexes from a siphonaceous marine green alga, Bryopsis Corticulans

Photosynthesis Research

2015123 (1) :61-76

SCI 

IF: 4.122

秦晓春

3

A stable ‘sandwich’ system of Surface-Enhanced Resonance Raman Scattering for the    analysis of β-carotenes in a        photosynthetic pigment-protein complex

Journal of Raman Spectroscopy

2013, 44 (8) :1111-1119

SCI

IF: 2.395

秦晓春

4

Spectral and functional studies on siphonaxanthin-type light harvesting complex of photosystem II from Bryopsis corticulans

Photosynthesis Research

2013, 117 (1) :267-279

SCI

IF: 4.122

秦晓春

5

Antimalarial diterpenoid dimers of a new carbon skeleton from Aphanamixis grandifolia

Org. Biomol. Chem.,

 2016, 14, 957–962

SCI

IF:3.562

张华

6

Himalensines A and B, Alkaloids from Daphniphyllum himalense

Org. Lett., 2016,

18, 1202–1205

SCI

IF:6.324

张华

7

New Alkaloids from Daphniphyllum himalense

RSC Adv., 2016,

 6, 44402–44409

SCI

IF:3.84

张华

8

Dammarane-type triterpenoids as 11β-HSD1 inhibitors from Homonoia riparia

Org. Biomol. Chem.,

 2014, 12, 4716-4722.

SCI

IF:3.562

张华

9

Limonoids and Triterpenoids as 11β-HSD1 Inhibitors from Walsura robusta

J. Nat. Prod.,

 2016, 79, 899–906.

SCI

IF:3.798

张华

10

Anti-HIV Alkaloids from Flueggea virosa

Org. Lett., 2015,

 17, 6274-6277

SCI

IF:6.324

张华

11

New Securinega alkaloids with anti-HIV activity from Flueggea virosa

RSC Adv., 2015,

 5, 107045-107053

SCI

IF:3.84

张华

12

Organic carbonates from natural sources

Chem. Rev., 2014,

 114, 883-898

SCI

IF:46.568

张华

13

Ricinodols A–G: new tetracyclic triterpenoids as11β-HSD1 inhibitors from Ricinodendron heudelotii

RSC Adv., 2015,

 5, 26777-26784

SCI

IF:3.84

张华

13

11β-HSD1 Inhibitors from Walsura cochinchinensis

J. Nat. Prod., 2013,

 76, 1319-1327

SCI

IF:3.798

张华

14

Fluevirosines A-C: A Biogenesis Inspired Example in the Discovery of New Bioactive Scaffolds from Flueggea virosa

Org. Lett., 2013,

15, 120–123

SCI

IF:6.324

张华

15

Genome-wide association study dissects the genetic architecture of oil biosynthesis in maize kernels.

Nature Genetics 

 2013, 45 (1) :43-50

SCI  IF:29.65

李慧

16

 An 11-bp insertion in Zea mays fatb reduces the palmitic acid content of fatty acids in maize grain.

PLoS One, 2011,

 6 (9) :e24699

SCI  IF:3.73

李慧

17

Heterogeneous nuclear ribonucleoprotein E1 regulates protein disulphide isomerase translation in oxidized low-density lipoprotein-activated endothelial cells.

Acta Physiol (Oxf).

2015,213(3):664-75.

SCI

IF:4.382

孟宁

18

Lipopolysaccharide induces autophagy through BIRC2 in human umbilical vein endothelial cells.

 J Cell Physiol.

 2010, 225(1):174-9

SCI

IF:5.5

孟宁

19

A butyrolactone derivative suppressed lipopolysaccharide-induced autophagic injury through inhibiting the autoregulatory loop of p8 and p53 in vascular endothelial cells.

 Int J Biochem Cell Biol.

 2012, 44(2):311-9.

SCI

IF:4.24

孟宁

20

Lipopolysaccharide induces autophagy through BIRC2 in human umbilical vein endothelial cells.

J Cell Physiol.

 2010, 225(1):174-9.

SCI IF:4.218

孟宁

21

Nano-Mg(OH)2-induced proliferation inhibition and dysfunction of human umbilical vein vascular endothelial cells through caveolin-1-mediated endocytosis.

Cell Biol Toxicol

2015, 31(1):15-27.

SCI IF:1.97

孟宁

22

A novel butyrolactone derivative inhibited smooth muscle cell migration and proliferation and maintained endothelial cell functions through selectively affecting Na, K-ATPase activity and mitochondria membrane potential during in vitro angiogenesis.

 J Cell Biochem.

2008,104(6):2123-30.

SCI IF:3.12

孟宁

23

 Protective effects of a synthesized butyrolactone derivative against chloroquine-induced autophagic vesicle accumulation and the disturbance of mitochondrial membrane potential and Na+,K+-ATPase activity in vascular endothelial cells.

Chem Res Toxicol.

 

2009, 22(3):471-5.

SCI IF:4.147

孟宁

24

Scavenger receptor B protects shrimp from bacteria by enhancing phagocytosis and regulating expression of antimicrobial peptides

Developmental

and

Comparative

 Immunology

51(1):10-21.

ISSN: 0145-305X

SCI

IF: 3.62

李殿香

25

Cloning and expression analysis of an o-methyltransferase (OMT) gene from Chinese shrimp, Fenneropenaeus chinensis.

Fish & Shellfish

 Immunol.

21:284-292. 2006

SCI

IF:2.674

李殿香

26

An activator of mTOR inhibits oxLDL-induced autophagy and apoptosis in vascular endothelial cells and restricts atherosclerosis in apolipoprotein E/ mice.

Sci Rep. 2014 , 

4 (4) :5519

SCI

IF:5.228

孟宁

27

Antagonistic Effects of a Mixture of Low-Dose Nonylphenol and Di-N-Butyl Phthalate (Monobutyl Phthalate) on the Sertoli Cells and Serum Reproductive Hormones in Prepubertal Male Rats In Vitro and In Vivo.   

PLos One, 2014, 9(3).

SCI

IF:3.234

胡杨

28

Mixture effects of nonylphenol and di-n-butyl phthalate (monobutylphthalate monobutylphthalate) on the tight junctions between Sertoli cells in male rats in vitro and in vivo

Experimental

and

Toxicologic Patholog,

 2014, 66(9) :445-454.

SCI IF:1.86

胡杨

29

Monobutyl phthalate induces the expression change of G-Protein-Coupled Receptor 30 in rat testicular Sertoli cells. Folia Histochemica et Cytobiologica.

Folia Histochemica

 Et Cytobiologica,

 2013, 51(1):18-24

SCI

IF:1.364

胡杨

30

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Detection of Nanoscale Soil Organic Matter by Middle Infrared Spectrum for Forensic Science

Journal of

 Chemistry,

2015, 

Article ID 189421.

SCI

IF: 0.772

李玉梅

 
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